Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 1.00 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3568197 | 0.86 | CNR1 (1.00) | CNR1CNR2KCNH2 | |
| SCHEMBL3169970 | 0.86 | CNR1 (0.77) | CNR1KCNH2 | |
| SCHEMBL3175835 | 0.84 | CNR1 (0.85) | CNR1CNR2KCNH2 | |
| SCHEMBL3188793 | 0.81 | CNR1 (0.87) | CNR1CNR2KCNH2 | |
| SCHEMBL3170037 | 0.80 | CNR1 (1.00) | CNR1CNR2KCNH2 | |
| SCHEMBL3180193 | 0.79 | CNR1 (0.80) | CNR1CNR2KCNH2 | |
| SCHEMBL3569011 | 0.78 | CNR1 (1.00) | CNR1CNR2KCNH2 | |
| SCHEMBL3570283 | 0.78 | CNR1 (0.82) | CNR1KCNH2 | |
| SCHEMBL3169302 | 0.77 | CNR1 (0.80) | CNR1CNR2KCNH2 | |
| SCHEMBL3521132 | 0.77 | CNR1 (1.00) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919471-B1 | (INDOL-3-YL)-HETEROCYCLE DERIVATIVES AS AGONISTS OF THE CANNABINOID CB1 RECEPTOR | MERCK SHARP & DOHME (NL) | 2014-01-08 | — | — | EP | disclosed |
| US-7763732-B2 | 7-Chloro-3-({5-[N-(morpholin-1-ylcarboxamido)methyl]aminomethyl}-([1,2,4]-thiadiazol-3-yl))-1-(tetrahydropyran-4-yl)methyl-1H-indole, hydrochloride salt; treatment of pain | N.V. ORGANON (NL) | 2010-07-27 | — | — | US | disclosed |