Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.53 |
| ▸ | FNTB | P49356 | 7/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681241 | 0.90 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL3519556 | 0.86 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL3688109 | 0.85 | PGGT1B (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL3518473 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL5548775 | 0.84 | FNTA (0.51) | FNTAFNTBPGGT1BRAF1MAP2K1 | |
| SCHEMBL3519588 | 0.84 | PGGT1B (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL5548779 | 0.84 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL3498367 | 0.77 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL3692429 | 0.75 | PGGT1B (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL3687061 | 0.74 | FNTA (0.85) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155197-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | Link Medicine Corporation (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008112525-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | LINK MEDICINE CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |