Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL5851785 | 0.83 | SLC22A12 (0.46) | HDAC6AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL1367446 | 0.83 | CA1 (0.52) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| Trifluoroacetic Acid SCHEMBL761111 | 0.79 | HDAC4 (0.48) | PPARGPPARAPDK2POLBSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3180617 | 0.77 | PPARG (0.47) | AKR1C3AKR1C2PPARGPPARAPDK2 | |
| SCHEMBL5851128 | 0.77 | TSHR (0.48) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL5851108 | 0.76 | SLC22A12 (0.39) | HDAC6AKR1C3AKR1C2KDM4EALDH1A1 | |
| Phenylmethanesulfonic Acid SCHEMBL5849921 | 0.74 | ELANE (0.43) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| Trifluoroacetic Acid SCHEMBL28188119 | 0.73 | NPC1 (0.50) | ALDH1A1HPGDHSD17B10CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL5005162 | 0.73 | HTT (0.64) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL17056215 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |