Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 16/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 13/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.70 |
| ▸ | NADK | O95544 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061415 | 0.83 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL5732373 | 0.83 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL31061173 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL3517750 | 0.80 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL3520300 | 0.79 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL13731182 | 0.79 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL17830246 | 0.69 | MEN1 (0.49) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL8832637 | 0.67 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL29439771 | 0.67 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL13731483 | 0.67 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219448-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | Myriad Pharmaceuticals, Inc. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009065035-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | MYRIAD GENETICS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |