SCHEMBL3520665

SCHEMBL3520665

CCC1(c2cccc(Oc3cc(Cc4ncc(C)[nH]4)ccc3C#N)c2)CCCCN(C)C1=O

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.74
FNTB P49356 20/20 0.74
PGGT1B P53609 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3502047 0.85 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL3498962 0.85 FNTA (0.77) FNTAFNTBPGGT1B
SCHEMBL3499215 0.85 FNTA (0.73) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7671931 0.85 FNTA (0.99) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7674246 0.84 FNTA (0.72) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7680161 0.84 FNTA (0.76) FNTAFNTBPGGT1B
SCHEMBL3501591 0.84 FNTA (0.71) FNTAFNTBPGGT1B
SCHEMBL3501949 0.82 FNTA (0.83) FNTAFNTBPGGT1B
SCHEMBL3499719 0.82 FNTA (0.75) FNTAFNTBPGGT1B
SCHEMBL3500843 0.82 FNTA (0.75) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155197-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES Link Medicine Corporation (US) 2010-02-24 EP disclosed
WO-2008112525-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES LINK MEDICINE CORPORATION (US) 2008-09-18 WO disclosed