Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.57 |
| ▸ | CCND1 | P24385 | 20/20 | 0.57 |
| ▸ | CCND3 | P30281 | 20/20 | 0.57 |
| ▸ | CDK6 | Q00534 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35210987 | 0.93 | CDK4 (0.61) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35210912 | 0.92 | CDK4 (0.56) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35211327 | 0.90 | CDK4 (0.58) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35210948 | 0.88 | CDK4 (0.53) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35210986 | 0.88 | CDK4 (0.52) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35210571 | 0.88 | CDK4 (0.53) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35211166 | 0.88 | CDK4 (0.61) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35211012 | 0.87 | CDK4 (0.52) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35210514 | 0.87 | CDK4 (0.52) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL35210681 | 0.86 | CDK4 (0.52) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125391-A1 | PYRIMIDINE INDOLES AS CDK4 INHIBITORS | INCYTE CORP (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125391-A1 | PYRIMIDINE INDOLES AS CDK4 INHIBITORS | CDK4, CCNA1, CCNO | CDK4 1/4885CCND1 18/4885CCND3 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.