Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688219 | 0.98 | TSHR (0.67) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL494299 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL494112 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL81128 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL1286873 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3502791 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3503395 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL494114 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL3503548 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL118000 | 0.87 | TSHR (0.82) | TSHRLMNAALDH1A1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102197-A1 | METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF | UNRAVEL BIOSCIENCES, INC. (US) | 2026-05-15 | — | — | WO | claimed |
| US-20260125343-A1 | METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF | UNRAVEL BIOSCIENCES INC (US) | 2026-05-07 | — | — | US | claimed |
| WO-2026102197-A1 | METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF | UNRAVEL BIOSCIENCES, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20260125343-A1 | METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF | UNRAVEL BIOSCIENCES INC (US) | 2026-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125343-A1 | METHODS FOR PREPARING HIGH-PURITY VORINOSTAT AND PRECURSORS THEREOF | HDAC8, HDAC7, SUB1 | TSHR 2908/4885LMNA 1860/4885ALDH1A1 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.