SCHEMBL35211418

SCHEMBL35211418

COc1cc2c3n(nc2c(F)c1Cl)CCN(C(=O)CN)[C@@H]3C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 4/20 0.32
▸ CFD P00746 12/20 0.32
▸ DPP4 P27487 2/20 0.31
▸ DPP7 Q9UHL4 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35211347 1.00 CCR1 (0.32) CCR1CFDDPP4DPP7MEN1
SCHEMBL35211306 0.91 KMT2A (0.35) CCR1CFDMEN1KMT2AEGFR
SCHEMBL35211434 0.91 KMT2A (0.32) CCR1CFDMEN1KMT2A
SCHEMBL35211047 0.91 KMT2A (0.32) CCR1CFDMEN1KMT2A
SCHEMBL35211486 0.91 KMT2A (0.32) CCR1CFDMEN1KMT2A
SCHEMBL35211078 0.85 DPP4 (0.33) DPP4EGFR
SCHEMBL35211102 0.83 TLR9 (0.35) CCR1EGFR
SCHEMBL35212060 0.83 CCR1 (0.33) CCR1MEN1KMT2AEGFR
SCHEMBL35212408 0.83 CCR1 (0.33) CCR1MEN1KMT2AEGFR
SCHEMBL35212409 0.83 CCR1 (0.33) CCR1MEN1KMT2AEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125384-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125384-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF CGAS, GMPS, PRKG1 CCR1 829/4885CFD 4692/4885DPP4 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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