SCHEMBL35212428

SCHEMBL35212428

Cc1c(F)ccc(F)c1-c1c(C(=O)N[C@@H](CC(N)=O)c2cccc(Cl)c2)c[nH]c1C(=O)c1ccc(CCOCCOCCO)cc1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DCAF1 Q9Y4B6 11/20 0.43
CNR2 P34972 1/20 0.34
MAPK1 P28482 8/20 0.34
AURKA O14965 1/20 0.34
CDK2 P24941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35212183 1.00 DCAF1 (0.43) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL35212462 1.00 DCAF1 (0.43) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL35212406 0.95 DCAF1 (0.42) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL35212451 0.93 DCAF1 (0.41) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL35211915 0.93 DCAF1 (0.41) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL30937313 0.92 DCAF1 (0.42) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL35211902 0.90 DCAF1 (0.41) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL27369934 0.87 DCAF1 (0.48) DCAF1CNR2MAPK1AURKACDK2
SCHEMBL30937280 0.86 DCAF1 (0.38) DCAF1CNR2MAPK1
SCHEMBL35212171 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 DCAF1 2314/4885CNR2 68/4885MAPK1 2997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.