Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523293 | 0.84 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL3522178 | 0.84 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL3518651 | 0.82 | MAPK14 (0.66) | MAPK14 | |
| SCHEMBL5269275 | 0.82 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL3520384 | 0.82 | MAPK14 (0.68) | MAPK14 | |
| SCHEMBL3523334 | 0.80 | MAPK14 (0.67) | MAPK14 | |
| SCHEMBL3523444 | 0.77 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL3526211 | 0.77 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL3526120 | 0.77 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL3520321 | 0.77 | MAPK14 (0.70) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795271-B2 | Substituted pyrimidinones | PHARMACIA CORPORATION (US) | 2010-09-14 | — | — | US | disclosed |