Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 4/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 11/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 11/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 9/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 9/20 | 0.47 |
| ▸ | PRKD2 | Q9BZL6 | 8/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 8/20 | 0.47 |
| ▸ | CSNK1G2 | P78368 | 6/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 6/20 | 0.47 |
| ▸ | MINK1 | Q8N4C8 | 6/20 | 0.47 |
| ▸ | CSNK1G3 | Q9Y6M4 | 5/20 | 0.47 |
| ▸ | CSNK1G1 | Q9HCP0 | 4/20 | 0.47 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523791 | 0.87 | MAPK9 (0.51) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3521273 | 0.85 | MAPK9 (0.62) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3519701 | 0.85 | MAPK9 (0.58) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3522612 | 0.84 | MAPK9 (0.58) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3524969 | 0.83 | CSNK1E (0.71) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3525223 | 0.83 | GRIA1 (0.55) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3525694 | 0.82 | CSNK1E (0.71) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3519582 | 0.80 | CSNK1E (0.50) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3529514 | 0.79 | MAPK9 (0.50) | CSNK1ECCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL3725128 | 0.79 | MAPK9 (0.64) | CSNK1ECCNA2CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709468-B2 | Imidazo based heterocycles | ABBOTT LABORATORIES (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070099925-A1 | Novel imidazo based heterocycles | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099925-A1 | Novel imidazo based heterocycles | CDK4, CDK2, MAP3K19 | CSNK1E 216/4885CCNA2 208/4885CDK2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.