SCHEMBL35233

SCHEMBL35233

[CH2]C(C)CC#CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8960502 0.78 GRIK1 (0.31)
SCHEMBL8960996 0.77
SCHEMBL8960604 0.76
SCHEMBL5985671 0.75
SCHEMBL6301594 0.73
SCHEMBL1760715 0.73
SCHEMBL8960666 0.73
SCHEMBL2121156 0.73
SCHEMBL9490377 0.71
SCHEMBL2122824 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 682 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037328-B2 Compounds containing benzo[d][1,3]oxathiole, benzo[d][1,3]oxathiole 3-oxide or benzo[d][1,3]oxathiole 3,3-dioxide and methods/uses thereof as agonists of G protein-coupled receptor 119 PRAMANA PHARMACEUTICALS INC. (CA) 2024-07-16 US disclosed
US-12029728-B2 Small molecules with anti-protozoan activity NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (US) 2024-07-09 US disclosed
EP-4387608-A1 PRODRUGS AND DERIVATIVES OF PSILOCIN AND USES THEREOF Terran Biosciences, Inc. (US) 2024-06-26 EP disclosed
EP-4384498-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER Onconova Therapeutics, Inc. (US) 2024-06-19 EP disclosed
CN-118119389-A Prodrugs and derivatives of des-phosphate nupharicin and uses thereof 人类生物科学股份有限公司 2024-05-31 CN disclosed
CN-118103357-A FABP4/5 inhibitors, methods of use and methods of preparation 塞洛拉姆股份有限公司 2024-05-28 CN disclosed
CN-118076583-A Methods and compositions for treating cancer 安可诺瓦治疗公司 2024-05-24 CN disclosed
WO-2024107730-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER ONCONOVA THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed
WO-2024107661-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER ONCONOVA THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed
US-20240158379-A1 NOVEL BENZOFURAN, BENZOTHIOPHENE, AND INDOLE ANALOGS THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE OLIGOMERIX, INC. 2024-05-16 US disclosed
EP-0693284-A1 PROSTACYCLIN-CONTAINING OLEAGINOUS OINTMENT TEIJIN LIMITED (JP) 1996-01-24 EP disclosed
EP-0664281-A1 ISOCARBACYCLIN WITH MODIFIED $g(a)-CHAIN AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1995-07-26 EP disclosed
EP-0634171-A1 PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS TEIJIN LIMITED (JP) 1995-01-18 EP disclosed
US-5364883-A Prostaglandins TEIJIN LIMITED (JP) 1994-11-15 US disclosed
EP-0330025-B1 Antidiabetic composition comprising isocarbacyclin derivative TEIJIN LTD (JP) 1994-10-12 EP disclosed
US-5159102-A Antiulcer agent TEIJIN LIMITED (JP) 1992-10-27 US disclosed
EP-0402477-A1 USE OF ISOCARBACYCLINS FOR PREVENTING OR TREATING ORGAN DISEASES TEIJIN LIMITED (JP) 1990-12-19 EP disclosed
EP-0330025-A2 Antidiabetic composition comprising isocarbacyclin derivative TEIJIN LIMITED (JP) 1989-08-30 EP disclosed
EP-0173754-B1 7-THIAPROSTAGLANDIN E 1?'S AND PROCESS FOR THEIR PREPARATION TEIJIN LIMITED (JP) 1989-04-26 EP disclosed
EP-0173754-A1 7-THIAPROSTAGLANDIN E 1?'S AND PROCESS FOR THEIR PREPARATION TEIJIN LIMITED (JP) 1986-03-12 EP disclosed