Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.47 |
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18247382 | 0.74 | CNR2 (0.39) | CNR1CNR2 | |
| SCHEMBL3523176 | 0.70 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL3524728 | 0.70 | CNR1 (0.44) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL3521099 | 0.70 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL3572781 | 0.70 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL3521097 | 0.70 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL3525599 | 0.67 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL3524296 | 0.66 | CHRNB4 (0.42) | CNR1LTA4H | |
| SCHEMBL4964598 | 0.66 | CHRNB4 (0.42) | CNR1LTA4H | |
| SCHEMBL3524292 | 0.66 | CHRNB4 (0.42) | CNR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772227-B2 | Tricyclic 1-[(indol-3-yl)carbonyl]piperazine derivatives as cannabinoid CB1 receptor agonists | N.V. ORGANON (NL) | 2010-08-10 | — | — | US | disclosed |
| EP-1696930-B1 | TRICYCLIC 1-((3-INDOL-3-YL)CARBONYL)PIPERAZINE DERIVATIVES AS CANNABINOID CB1 RECEPTOR AGONISTS | ORGANON NV (NL) | 2007-04-11 | — | — | EP | disclosed |