Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ampicillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TEK | Q02763 | 1/20 | 1.00 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 0.98 |
| ▸ | TSHR | P16473 | 2/20 | 0.98 |
| ▸ | RARB | P10826 | 1/20 | 0.84 |
| ▸ | RARG | P13631 | 1/20 | 0.84 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.84 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.84 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.82 |
| ▸ | GLA | P06280 | 1/20 | 0.82 |
| ▸ | BLM | P54132 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ampicillin SCHEMBL3467975 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL14148474 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL11985596 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL9528765 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL2282070 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL13014516 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL24312533 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL13240124 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL15577318 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB | |
| Ampicillin SCHEMBL22380861 | 1.00 | KDM4E (1.00) | KDM4ERECQLHPGDTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 347682 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119185146-A | Spray with moisturizing function and preparation method thereof | 南京任亢盈医药科技有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119082072-A | Transpeptidase mutant and preparation method and application thereof | 修实生物医药(南通)有限公司 | 2024-12-06 | — | — | CN | claimed |
| US-12158467-B2 | Method for testing of antibiotic susceptibility in microorganisms | MODULE INNOVATIONS PRIVATE LIMITED (IN) | 2024-12-03 | — | — | US | claimed |
| CN-117448297-B | PET degrading enzyme PET-mh183/208Mutant and coding gene, engineering bacteria and application thereof | 源天生物科技(天津)有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-113423430-B | Amatoxin conjugates containing branched linkers | 杭州多禧生物科技有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-117431272-B | Construction method and application of CX3CL1 lentiviral recombinant vector stably and overexpressed in primary intramuscular fat cells of chickens | 江苏省家禽科学研究所 | 2024-11-29 | — | — | CN | claimed |
| WO-2024240216-A1 | PHARMACEUTICAL COMPOSITION FOR EFFECTIVELY DELAYING AND TREATING MYOPIA | 温州医科大学附属眼视光医院 | 2024-11-28 | — | — | WO | claimed |
| US-20240390364-A1 | Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions | REID CHRISTOPHER BRIAN (US) | 2024-11-28 | — | — | US | claimed |
| US-20240390432-A1 | ENGINEERED VECTORS AND ORGANISMS CONTAINING THE SAME FOR ISOFLAVONE CONVERSION IN THE GUT | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-11-28 | — | — | US | claimed |
| WO-2024239281-A1 | TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE | HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) | 2024-11-28 | — | — | WO | claimed |
| US-4122158-A | FOR TREATMENT OF BURNS; BIODEGRADABLE HYDROPHOBIC POLYMER; SUSTAINED RELEASE | ALZA CORPORATION (US) | 1978-10-24 | — | — | US | claimed |
| US-4113856-A | OBTAINED BY FERMENTATION, SYNERGISM | BEECHAM GROUP LIMITED (GB) | 1978-09-12 | — | — | US | claimed |
| US-4073687-A | PENICILLINS OR CEPHALOSPORINS | SHIONOGI & CO., LTD. (JA) | 1978-02-14 | — | — | US | claimed |
| US-4066640-A | METHAMPICILLIN LYSINATE AND ITS METHOD OF MANUFACTURE | KIM YOUNG SUL | 1978-01-03 | — | — | US | claimed |
| US-4024268-A | Use of ampicillin for the treatment of swine dysentery | E. R. SQUIBB & SONS, INC. (US) | 1977-05-17 | — | — | US | claimed |
| US-3996355-A | SACCHARIDE, VEGETABLE OIL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-12-07 | — | — | US | claimed |
| US-3993753-A | DEXTROSE, GALACTOSE, AND SODIUM CHLORIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-11-23 | — | — | US | claimed |
| US-3983209-A | HYDROPHOBIC BIOERODIBLE POLYMER, MICROBIOCIDE OR PROTEOLYTIC ENZYME | ALZA CORPORATION (US) | 1976-09-28 | — | — | US | claimed |
| US-3937655-A | Method for preparing stable β-lactam-type-antibiotic susceptibility test discs | ELI LILLY AND COMPANY (US) | 1976-02-10 | — | — | US | claimed |
| US-3931150-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-01-06 | — | — | US | claimed |