Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.68 |
| ▸ | PPARD | Q03181 | 6/20 | 0.68 |
| ▸ | PPARA | Q07869 | 6/20 | 0.68 |
| ▸ | F7 | P08709 | 6/20 | 0.68 |
| ▸ | F3 | P13726 | 6/20 | 0.68 |
| ▸ | TERT | O14746 | 3/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | FABP4 | P15090 | 3/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.68 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.68 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL3527457 | 1.00 | PPARG (0.68) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL11169925 | 0.98 | PPARG (0.70) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL11169918 | 0.98 | PPARG (0.70) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28412739 | 0.97 | PPARG (0.68) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL11175491 | 0.97 | PPARG (0.68) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL11175477 | 0.97 | PPARG (0.68) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL5270878 | 0.97 | PPARG (0.68) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL5270864 | 0.97 | PPARG (0.68) | PPARGPPARDPPARAF7F3 | |
| Linoleic Acid SCHEMBL2693995 | 0.96 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Terephthalic Acid SCHEMBL28326625 | 0.92 | PPARG (0.74) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10150931-B2 | Grease compositions comprising estolide base oils | BIOSYNTHETIC TECHNOLOGIES, LLC (US) | 2018-12-11 | — | — | US | disclosed |
| US-20170233676-A1 | Grease Compositions Comprising Estolide Base Oils | BIOSYNTHETIC TECHNOLOGIES LLC (US) | 2017-08-17 | — | — | US | disclosed |
| US-9605231-B2 | Grease compositions comprising estolide base oils | BIOSYNTHETIC TECHNOLOGIES, LLC (US) | 2017-03-28 | — | — | US | disclosed |
| US-20160281023-A1 | Grease Compositions Comprising Estolide Base Oils | BIOSYN HOLDINGS, LLC | 2016-09-29 | — | — | US | disclosed |
| US-9394501-B2 | Grease compositions comprising estolide base oils | BIOSYNTHETIC TECHNOLOGIES, LLC (US) | 2016-07-19 | — | — | US | disclosed |
| EP-2702122-A1 | GREASE COMPOSITIONS COMPRISING ESTOLIDE BASE OILS | Biosynthetic Technologies, LLC (US) | 2014-03-05 | — | — | EP | disclosed |
| US-20120322707-A1 | GREASE COMPOSITIONS COMPRISING ESTOLIDE BASE OILS | BIOSYN HOLDINGS, LLC | 2012-12-20 | — | — | US | disclosed |
| WO-2012173665-A1 | GREASE COMPOSITIONS COMPRISING ESTOLIDE BASE OILS | LUBRIGREEN BIOSYNTHETICS, LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| EP-2205707-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | Chevron U.S.A., Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009042507-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | CHEVRON U.S.A. INC. (US) | 2009-04-02 | — | — | WO | disclosed |
| US-20090088353-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | CHEVRON U.S.A. INC. | 2009-04-02 | — | — | US | disclosed |
| US-20090088354-A1 | LUBRICATING GREASE COMPOSITION AND PREPARATION | CHEVRON U.S.A. INC. | 2009-04-02 | — | — | US | disclosed |
| US-20070238625-A1 | Grease Composition And Additive For Improving Bearing Life | AFTON CHEMICAL CORPORATION | 2007-10-11 | — | — | US | disclosed |
| EP-1842897-A1 | Grease composition and additive for improving bearing life | Afton Chemical Corporation (US) | 2007-10-10 | — | — | EP | disclosed |
| US-5037563-A | Addition of calcium oxide | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-08-06 | — | — | US | disclosed |