Valienamine

Valienamine

SCHEMBL352747

NC1C=C(CO)C(O)C(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MGAM O43451 4/20 1.00
SI P14410 2/20 1.00
FUCA1 P04066 1/20 0.52
GLB1 P16278 2/20 0.42
GBA1 P04062 1/20 0.42
CDA P32320 1/20 0.40
TREH O43280 1/20 0.38
AHCY P23526 3/20 0.36
EZH2 Q15910 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valienamine SCHEMBL3960550 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14408654 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14409002 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14408836 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14416123 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14408647 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14193749 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14408472 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL12955939 1.00 MGAM (1.00) MGAMSIFUCA1GLB1GBA1
Valienamine SCHEMBL14408468 0.85 MGAM (0.73) MGAMSIFUCA1GLB1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 694 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463445-B1 COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DISEASES ASSOCIATED WITH IMPAIRED ?-GALACTOSIDASE ACTIVITY DORPHAN S A (CH) 2025-10-01 EP claimed
CN-119677539-A Combination therapy for modulating lipid production 俄亥俄州创新基金会 2025-03-21 CN claimed
CN-118786120-A Compounds and their use for the treatment of diseases associated with impaired beta-galactosidase activity 多尔潘股份公司 2024-10-15 CN claimed
CN-118000046-B Organic plant nutrient soil and preparation method thereof 宁夏大彩生物科技有限公司 2024-08-16 CN claimed
WO-2023172669-A9 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2024-08-02 WO claimed
CN-118000046-A Organic plant nutrient soil and preparation method thereof 宁夏大彩生物科技有限公司 2024-05-10 CN claimed
CN-114908130-B Method for preparing aminosugar intermediate valienamine by enzyme method and application thereof 上海凡秦医药科技有限公司 2024-02-06 CN claimed
CN-117298177-B Natural immunomodulator and preparation method thereof 暨南大学 2024-02-02 CN claimed
CN-117298177-A Natural immunomodulator and preparation method thereof 暨南大学 2023-12-29 CN claimed
WO-2023172669-A2 COMBINATION THERAPIES FOR MODULATION OF LIPID PRODUCTION OHIO STATE INNOVATION FOUNDATION (US) 2023-09-14 WO claimed
EP-1009398-A1 MOLECULAR COMPLEX AND CONTROL-RELEASE OF ALPHA HYDROXYACIDS Yu, Ruey J., Dr. (US) 2000-06-21 EP claimed
WO-2000018949-A2 DELIVERY OF PHOSPHOINOSITIDE POLYPHOSPHATES INTO CELLS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2000-04-06 WO claimed
US-5929037-A GLUCOSIDASE I INHIBITORS ALBERTA RESEARCH COUNCIL (CA) 1999-07-27 US claimed
US-5877212-A HYDROGEN BONDING WITH COMPLEXING AGENT YU RUEY J (US) 1999-03-02 US claimed
WO-1998046217-A1 MOLECULAR COMPLEX AND CONTROL-RELEASE OF ALPHA HYDROXYACIDS YU RUEY J (US) 1998-10-22 WO claimed
EP-0837867-A1 MODIFIED $g(a)-D-Glcp-(1-2)-$g(a)-D-Glcp-(1-3)-$g(a)-D-Glcp-ANALOGUES ALBERTA RESEARCH COUNCIL (CA) 1998-04-29 EP claimed
WO-1996040700-A1 MODIFIED α-D-Glcp-(1-2)-α-D-Glcp-(1-3)-α-D-Glcp-ANALOGUES ALBERTA RESEARCH COUNCIL (CA) 1996-12-19 WO claimed
US-5169767-A Culture product of Sclerotium promoted by validamycin TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-08 US claimed
EP-0049981-B1 VALIENAMINE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1984-07-25 EP claimed
EP-0049981-A1 Valienamine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-04-21 EP claimed