⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660494 | 0.94 | — | — | |
| SCHEMBL319580 | 0.75 | — | — | |
| SCHEMBL129408 | 0.75 | — | — | |
| SCHEMBL13879062 | 0.69 | CYP2A6 (0.62) | — | |
| SCHEMBL38660079 | 0.69 | — | — | |
| SCHEMBL14666897 | 0.64 | MAPT (0.32) | — | |
| SCHEMBL21720519 | 0.63 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL19881200 | 0.63 | — | — | |
| SCHEMBL4026792 | 0.63 | — | — | |
| SCHEMBL9631841 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-11-21 | — | — | US | claimed |
| CN-118591529-A | Deuterated ROCK inhibitors, pharmaceutical compositions and therapeutic applications | 维眸生物科技(浙江)有限公司 | 2024-09-03 | — | — | CN | claimed |
| US-20150093435-A1 | TREATMENT OF LENGTH DEPENDENT NEUROPATHY | ARC1, INC. | 2015-04-02 | — | — | US | claimed |
| US-8026266-B2 | Treatment of length dependent neuropathy | ARCION THERAPEUTICS, INC. (US) | 2011-09-27 | — | — | US | claimed |
| US-20110142920-A1 | TREATMENT OF LENGTH DEPENDENT NEUROPATHY | ARCION THERAPEUTICS, INC. | 2011-06-16 | — | — | US | claimed |
| US-RE41998-E1 | Compositions and methods of treatment of sympathetically maintained pain | Arclon Therapeutics, Inc. (US) | 2010-12-14 | — | — | US | claimed |
| EP-1962836-A2 | TREATMENT OF LENGTH DEPENDENT NEUROPATHY | Arcion Therapeutics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| CN-101237867-A | Novel 4-amino-thieno[3,2-C]pyridine-7-carboxylic acid amides | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | CN | claimed |
| US-20070142385-A1 | TREATMENT OF LENGTH DEPENDENT NEUROPATHY | ARC1, INC. | 2007-06-21 | — | — | US | claimed |
| WO-2007056460-A2 | TREATMENT OF LENGTH DEPENDENT NEUROPATHY | ARCION THERAPEUTICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| US-4526962-A | Cephalosporin derivatives | RHONE-POULENC SANTE (FR) | 1985-07-02 | — | — | US | claimed |
| CN-117177975-B | Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | UNIVERSITE DE MONTREAL (CA) | 2025-11-25 | — | — | US | disclosed |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2025-08-28 | — | — | US | disclosed |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | Université de Montréal (CA) | 2024-11-12 | — | — | US | disclosed |
| US-6559186-B1 | Pain is treated topically by administering to the site where sympathetically maintained pain is present an alpha -1-adrenergic antagonist, alpha -2- adrenergic agonist, or other drug that depletes or blocks synthesis of sympathetic | ARC 1, INC. | 2003-05-06 | — | — | US | disclosed |
| EP-0573581-A4 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1 INC (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0573581-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1, Inc. (US) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992014453-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1, INC. (US) | 1992-09-03 | — | — | WO | disclosed |
| US-4526962-A | Cephalosporin derivatives | RHONE-POULENC SANTE (FR) | 1985-07-02 | — | — | US | disclosed |