Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 13/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | POU2F2 | P09086 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185698 | 0.90 | SLC22A2 (0.48) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL3523656 | 0.86 | SLC22A2 (0.51) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL2185540 | 0.84 | SLC22A2 (0.50) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL3528399 | 0.84 | SLC22A2 (0.49) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL3522687 | 0.84 | SLC22A2 (0.49) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL2186514 | 0.83 | SLC22A2 (0.49) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL2187053 | 0.82 | SLC22A2 (0.48) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL2213631 | 0.81 | SLC22A2 (0.46) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL3527644 | 0.81 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2POU2F2 | |
| SCHEMBL3524900 | 0.81 | SLC22A2 (0.48) | SLC22A2CYP3A4TMEM97ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858788-B2 | Bicyclic carbamoylpyridone derivative having HIV integrase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |