SCHEMBL3528669

SCHEMBL3528669

COC(=O)c1cc(N)c(F)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.53
ABL1 P00519 1/20 0.51
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 5/20 0.45
MAPT P10636 4/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
GLA P06280 2/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
ATM Q13315 1/20 0.45
CFTR P13569 3/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NQO2 P16083 3/20 0.43
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3336996 0.86 GAA (0.61) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL31508307 0.86 GAA (0.61) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL9793695 0.85 GAA (0.59) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL1110997 0.85 GAA (0.57) GAAABL1MAPTHPGDLMNA
SCHEMBL2897626 0.84 GAA (0.62) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL3529864 0.84 KDM4E (0.50) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL30221910 0.84 KDM4E (0.50) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL30697733 0.84 GAA (0.67) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL1787222 0.84 GAA (0.67) GAAABL1KDM4EALDH1A1MAPT
SCHEMBL30508547 0.82 CA1 (0.51) GAAKDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040310-A Improved synthesis process of 2-chloro-4-fluoro-5-aminobenzoic acid methyl ester 大连奇凯医药科技有限公司 2025-05-27 CN claimed
CN-118324699-A Preparation method of saflufenacil 浙江中山化工集团股份有限公司 2024-07-12 CN claimed
CN-120040310-A Improved synthesis process of 2-chloro-4-fluoro-5-aminobenzoic acid methyl ester 大连奇凯医药科技有限公司 2025-05-27 CN disclosed
CN-120040310-A Improved synthesis process of 2-chloro-4-fluoro-5-aminobenzoic acid methyl ester 大连奇凯医药科技有限公司 2025-05-27 CN disclosed
CN-120040310-A Improved synthesis process of 2-chloro-4-fluoro-5-aminobenzoic acid methyl ester 大连奇凯医药科技有限公司 2025-05-27 CN disclosed
CN-119613399-A Tetra-substituted benzoate compound containing alkoxy acetate substituent and application thereof 江西天宇化工有限公司 2025-03-14 CN disclosed
CN-115124476-B Preparation method of herbicide intermediate 南京正荣医药化学有限公司 2024-09-20 CN disclosed
CN-118324699-A Preparation method of saflufenacil 浙江中山化工集团股份有限公司 2024-07-12 CN disclosed
CN-118324699-A Preparation method of saflufenacil 浙江中山化工集团股份有限公司 2024-07-12 CN disclosed
CN-117603147-A N-phenyl triazinone derivative and preparation method and application thereof 贵州大学 2024-02-27 CN disclosed
CN-117486818-A N-phenyl thiotriazinone derivative and preparation method and application thereof 贵州大学 2024-02-02 CN disclosed
EP-0745084-A1 HERBICIDAL TRICYCLIC HETEROCYCLES AND BICYCLIC UREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-04 EP disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
WO-1995022547-A1 HERBICIDAL TRICYCLIC HETEROCYCLES AND BICYCLIC UREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-24 WO disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
EP-0415641-B1 Substituted glutaramic acids and derivatives ROHM & HAAS (US) 1994-01-19 EP disclosed
US-5238908-A HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES ROHM AND HAAS COMPANY (US) 1993-08-24 US disclosed
EP-0415641-A1 Substituted glutaramic acids and derivatives ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed