Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 6/20 | 0.37 |
| ▸ | CDK2 | P24941 | 6/20 | 0.37 |
| ▸ | FLT3 | P36888 | 5/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530211 | 1.00 | CCNE1 (0.37) | CCNE1CDK2FLT3CCNT1MAPKAPK2 | |
| SCHEMBL3530208 | 1.00 | CCNE1 (0.37) | CCNE1CDK2FLT3CCNT1MAPKAPK2 | |
| SCHEMBL3529122 | 0.84 | CCNE1 (0.41) | CCNE1CDK2FLT3CCNT1MAPKAPK2 | |
| SCHEMBL3529117 | 0.84 | CCNE1 (0.41) | CCNE1CDK2FLT3CCNT1MAPKAPK2 | |
| SCHEMBL3006550 | 0.82 | KDM4E (0.37) | KDM4ENPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3006554 | 0.82 | KDM4E (0.37) | KDM4ENPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3527158 | 0.82 | CCNE1 (0.39) | CCNE1CDK2FLT3CCNT1MAPKAPK2 | |
| SCHEMBL3527159 | 0.82 | CCNE1 (0.39) | CCNE1CDK2FLT3CCNT1MAPKAPK2 | |
| SCHEMBL3026837 | 0.82 | TYK2 (0.47) | CCNE1CDK2FLT3CCNT1AXL | |
| SCHEMBL3026839 | 0.82 | TYK2 (0.47) | CCNE1CDK2FLT3CCNT1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723336-B2 | Fused heterocyclic compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080045536-A1 | FUSED HETEROCYCLIC COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045536-A1 | FUSED HETEROCYCLIC COMPOUNDS USEFUL AS KINASE MODULATORS | MAP3K3, MAP3K2, MAP4K3 | CCNE1 538/4885CDK2 67/4885FLT3 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.