SCHEMBL3533639

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11743033	0.86	MAPT (0.38)	CYP3A4CYP1A2CYP2D6CYP2C19MEN1
	SCHEMBL6987564	0.81	CYP3A4 (0.41)	CYP3A4CYP1A2CYP2D6CYP2C19MEN1
	SCHEMBL13405938	0.79	CSNK2A1 (0.48)	MEN1KMT2ACSNK2A1ALDH1A1HPGD
	SCHEMBL7618640	0.77	MAPT (0.41)	CYP3A4CYP1A2CYP2D6CYP2C19MEN1
	SCHEMBL2382336	0.77	MAPT (0.45)	CYP3A4CYP1A2CYP2D6CYP2C19MEN1
	SCHEMBL1465723	0.77	TAAR1 (0.34)	ALDH1A1TSHRGAAMAPTHTT
	SCHEMBL29360916	0.77	MAPT (0.45)	CYP3A4CYP1A2CYP2D6CYP2C19MEN1
	SCHEMBL11693833	0.77	MAPT (0.38)	CYP3A4CYP1A2CYP2D6CYP2C19MEN1
	SCHEMBL18932097	0.77	CSNK2A1 (0.47)	MEN1KMT2ACSNK2A1ALDH1A1HPGD
	SCHEMBL1520657	0.75	CYP3A4 (0.44)	CYP3A4CYP1A2CYP2D6CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.