SCHEMBL3533969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3529654	0.89	AURKA (0.49)	AURKANTRK1JAK2KCNH2CDK2
	SCHEMBL3533747	0.85	AURKA (0.43)	AURKANTRK1JAK2KCNH2CDK2
	SCHEMBL3535774	0.84	NTRK1 (0.49)	NTRK1ITKKDM4EALDH1A1LMNA
	SCHEMBL3476153	0.84	AURKA (0.56)	AURKAJAK2KCNH2HPGDKDM4E
	SCHEMBL3528812	0.83	NTRK1 (0.46)	AURKANTRK1CDK2ITKMET
	Hydrochloric Acid SCHEMBL3535629	0.83	AURKA (0.55)	AURKAJAK2KCNH2HPGDKDM4E
	SCHEMBL1704873	0.82	AURKA (0.54)	AURKANTRK1JAK2KCNH2
	SCHEMBL1704576	0.82	AURKA (0.54)	AURKANTRK1JAK2KCNH2
	SCHEMBL13955424	0.82	AURKA (0.52)	AURKANTRK1JAK2KCNH2CDK2
	Hydrochloric Acid SCHEMBL3531596	0.82	AURKA (0.53)	AURKANTRK1JAK2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.