SCHEMBL3534613

SCHEMBL3534613

COC(=O)COc1ccc(SCCCc2ccc3c(c2)Cc2cc(CCCSc4ccc(OCC(=O)OC)c(C)c4)ccc2-3)cc1C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 8/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PPARA Q07869 2/20 0.39
TSHR P16473 2/20 0.39
PPARG P37231 1/20 0.39
ALOX15 P16050 1/20 0.39
RAB9A P51151 1/20 0.38
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3534691 0.96 PPARD (0.47) PPARDPPARA
SCHEMBL3537320 0.90 PPARD (0.52) PPARDPPARA
SCHEMBL6279154 0.89 PPARD (0.36) PPARDPPARAPPARG
SCHEMBL3533135 0.84 PPARD (0.46) PPARDPPARAPPARG
SCHEMBL14364231 0.83 MEN1 (0.50) PPARDMEN1KMT2APPARATSHR
SCHEMBL3533021 0.81 PPARD (0.50) PPARDPPARAPPARG
SCHEMBL5633318 0.78 PPARD (0.42) PPARDMEN1KMT2APPARATSHR
SCHEMBL5633320 0.78 PPARD (0.42) PPARDMEN1KMT2APPARATSHR
SCHEMBL3534733 0.74 PLA2G4B (0.48) PPARDPPARATSHRPPARGALOX15
SCHEMBL3541424 0.73 PPARD (0.55) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040259950-A1 Novel compounds, their preparation and use HIGH POINT PHARMACEUTICALS, LLC 2004-12-23 US claimed
US-7816385-B2 Dimeric dicarboxylic acid derivatives, their preparation and use HIGH POINT PHARMACEUTICALS, LLC (US) 2010-10-19 US disclosed
US-7816385-B2 Dimeric dicarboxylic acid derivatives, their preparation and use HIGH POINT PHARMACEUTICALS, LLC (US) 2010-10-19 US disclosed
US-7816385-B2 Dimeric dicarboxylic acid derivatives, their preparation and use HIGH POINT PHARMACEUTICALS, LLC (US) 2010-10-19 US disclosed
EP-1578716-A1 DICARBOXYLIC ACID DERIVATIVES AS PPAR-AGONISTS NOVO NORDISK A/S (DK) 2005-09-28 EP disclosed
US-20040259950-A1 Novel compounds, their preparation and use HIGH POINT PHARMACEUTICALS, LLC 2004-12-23 US disclosed
WO-2004056740-A1 DICARBOXYLIC ACID DERIVATIVES AS PPAR-AGONISTS NOVO NORDISK A/S (DK) 2004-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259950-A1 Novel compounds, their preparation and use PPARG, PPARA, PPARD PPARD 3/4885MEN1 4854/4885KMT2A 3999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.