Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14253861 | 0.86 | NR1H4 (0.72) | NR1H4 | |
| SCHEMBL2128869 | 0.85 | NR1H4 (0.62) | NR1H4LIFR | |
| SCHEMBL2128592 | 0.83 | NR1H4 (0.80) | NR1H4LIFR | |
| SCHEMBL2129046 | 0.82 | NR1H4 (0.69) | NR1H4LIFR | |
| SCHEMBL4837149 | 0.82 | NR1H4 (0.66) | NR1H4LIFR | |
| SCHEMBL2128407 | 0.81 | NR1H4 (0.73) | NR1H4LIFR | |
| SCHEMBL2128864 | 0.80 | NR1H4 (0.67) | NR1H4LIFR | |
| SCHEMBL2129745 | 0.80 | NR1H4 (0.64) | NR1H4LIFR | |
| SCHEMBL2129864 | 0.78 | NR1H4 (0.60) | NR1H4LIFR | |
| SCHEMBL19506059 | 0.77 | NR1H4 (0.68) | NR1H4LIFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084147-B1 | HETEROCYCLIC FXR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2008025540-A1 | HETEROCYCLIC FXR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2008-03-06 | — | — | WO | disclosed |