⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353862 | 1.00 | — | — | |
| SCHEMBL3437088 | 1.00 | — | — | |
| SCHEMBL463486 | 1.00 | — | — | |
| SCHEMBL353861 | 1.00 | — | — | |
| SCHEMBL9680776 | 0.87 | — | — | |
| SCHEMBL9680769 | 0.87 | — | — | |
| SCHEMBL9679842 | 0.87 | — | — | |
| SCHEMBL9679837 | 0.87 | — | — | |
| SCHEMBL14568578 | 0.82 | — | — | |
| SCHEMBL16638826 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981919-B2 | HIV replication inhibiting pyrimidines | JANSSEN PHARMACEUTICAL N.V. (BE) | 2018-05-29 | — | — | US | disclosed |
| US-20170320835-A1 | HIV REPLICATION INHIBITING PYRIMIDINES | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-09 | — | — | US | disclosed |
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | disclosed |
| US-20170121292-A1 | HIV REPLICATION INHIBITING PYRIMIDINES | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-04 | — | — | US | disclosed |
| US-9580392-B2 | HIV replication inhibiting pyrimidines | JANSSEN PHARMACEUTICA NV (BE) | 2017-02-28 | — | — | US | disclosed |
| US-9321775-B2 | Compositions and methods for the treatment of moderate to severe pain | CELLIX BIO PRIVATE LIMITED (IN) | 2016-04-26 | — | — | US | disclosed |
| US-20150141479-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MODERATE TO SEVERE PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2015-05-21 | — | — | US | disclosed |
| US-20140343006-A1 | HIV Replication Inhibiting Pyrimidines | JANSSEN PHARMACEUTICA NV (NL) | 2014-11-20 | — | — | US | disclosed |
| US-8486534-B2 | Surface-modified polymer films | BAR-ILAN UNIVERSITY (IL) | 2013-07-16 | — | — | US | disclosed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120076835-A1 | HIV INHIBITING PYRIMIDINES DERIVATIVES | GUILLEMONT JEROME EMILE GEORGES (FR) | 2012-03-29 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
| US-8080551-B2 | HIV inhibiting pyrimidines derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-12-20 | — | — | US | disclosed |
| US-20110306722-A1 | SURFACE-MODIFIED POLYMER FILMS | BAR-ILAN UNIVERSITY (IL) | 2011-12-15 | — | — | US | disclosed |
| EP-2298761-A1 | HIV inhibiting pyrimidines derivatives | Janssen Pharmaceutica NV (BE) | 2011-03-23 | — | — | EP | disclosed |
| US-7589081-B2 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-7579343-B2 | Pyrrolo-thiazines and processes for the preparation and use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-08-25 | — | — | US | disclosed |
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA AG (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070055062-A1 | Pyrrolo-thiazines and processes for the preparation and use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-03-08 | — | — | US | disclosed |