Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.55 |
| ▸ | PLAU | P00749 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 2/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370912 | 0.89 | NR4A2 (0.63) | NR4A2CYP2C9ALDH1A1EGLN1RAB9A | |
| SCHEMBL3368278 | 0.89 | NR4A2 (0.65) | NR4A2CYP2C9EGLN1RAB9ANPC1 | |
| SCHEMBL3368404 | 0.88 | NR4A2 (0.64) | NR4A2CYP2C9ALDH1A1EGLN1RAB9A | |
| SCHEMBL3366318 | 0.87 | NR4A2 (0.63) | NR4A2CYP2C9EGLN1RAB9ANPC1 | |
| SCHEMBL3367821 | 0.86 | EGLN1 (0.73) | NR4A2CYP2C9ALDH1A3EGLN1PLAU | |
| SCHEMBL3367633 | 0.86 | CYP2C9 (0.64) | NR4A2CYP2C9ALDH1A1EGLN1RAB9A | |
| SCHEMBL3366348 | 0.84 | CYP2C9 (0.73) | NR4A2CYP2C9EGLN1RAB9ANPC1 | |
| SCHEMBL3367808 | 0.84 | EGLN1 (0.72) | NR4A2CYP2C9ALDH1A1EGLN1RAB9A | |
| SCHEMBL3369748 | 0.83 | EGLN1 (0.71) | NR4A2CYP2C9EGLN1RAB9ANPC1 | |
| SCHEMBL3369742 | 0.81 | NR4A2 (0.58) | NR4A2CYP2C9EGLN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704989-B2 | Derivatives of imidazo[1,2-a]pyridine-2-carboxamides, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-27 | — | — | US | claimed |
| US-20090149441-A1 | DERIVATIVES OF IMIDAZO[1,2-a]PYRIDINE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2009-06-11 | — | — | US | claimed |
| US-8404848-B2 | Derivatives of imidazo[1,2-a]pyridine-2-carboxamides, preparation method thereof and use of same in therapeutics | SANOFI (FR) | 2013-03-26 | — | — | US | disclosed |
| US-7704989-B2 | Derivatives of imidazo[1,2-a]pyridine-2-carboxamides, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-27 | — | — | US | disclosed |
| US-20090149441-A1 | DERIVATIVES OF IMIDAZO[1,2-a]PYRIDINE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149441-A1 | DERIVATIVES OF IMIDAZO[1,2-a]PYRIDINE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | NR4A2, NR4A3, NCOR1 | NR4A2 1/4885CYP2C9 2834/4885ALDH1A1 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.