Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 2/20 | 0.54 |
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241082 | 0.93 | SLC6A2 (0.71) | SLC6A2SLC6A4TSHRALDH1A1LMNA | |
| SCHEMBL941899 | 0.81 | SLC6A2 (0.79) | SLC6A2SLC6A4TSHRALDH1A1LMNA | |
| SCHEMBL7824827 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4TSHRALDH1A1LMNA | |
| SCHEMBL6427944 | 0.81 | MEN1 (0.61) | SLC6A2SLC6A4TSHRALDH1A1LMNA | |
| SCHEMBL20139887 | 0.81 | ATM (0.46) | SLC6A2SLC6A4TSHRALDH1A1LMNA | |
| SCHEMBL9967187 | 0.80 | BPTF (0.67) | SLC6A2SLC6A4ALDH1A1MAPTHRH3 | |
| SCHEMBL14175711 | 0.80 | NOTUM (0.50) | SLC6A2SLC6A4TSHRALDH1A1LMNA | |
| SCHEMBL720691 | 0.80 | NOTUM (0.54) | SLC6A2SLC6A4ALDH1A1MAPTHRH3 | |
| SCHEMBL4396441 | 0.80 | DPP4 (0.51) | SLC6A2SLC6A4ALDH1A1MAPTHRH3 | |
| SCHEMBL10178032 | 0.80 | BPTF (0.67) | SLC6A2SLC6A4ALDH1A1MAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732473-B2 | Compounds with nootropic action, their preparation, pharmaceutical compositions containing them, and use thereof | NEUROTUNE AG (CH) | 2010-06-08 | — | — | US | disclosed |
| US-20090163565-A1 | Compounds with nootropic action, their preperation, pharmaceutical compositions containing them, and use thereof | FARINA CARLO | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163565-A1 | Compounds with nootropic action, their preperation, pharmaceutical compositions containing them, and use thereof | OPRL1, GRIN3B, GRIN3A | SLC6A2 212/4885SLC6A4 238/4885TSHR 3915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.