Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544835 | 0.86 | GCK (0.43) | GCK | |
| SCHEMBL3541974 | 0.83 | GCK (0.43) | GCK | |
| SCHEMBL3548631 | 0.83 | GCK (0.52) | GCK | |
| SCHEMBL3550710 | 0.83 | GCK (0.51) | GCK | |
| SCHEMBL3541075 | 0.82 | GCK (0.42) | GCK | |
| SCHEMBL3551547 | 0.77 | GCK (0.47) | GCK | |
| SCHEMBL2645285 | 0.75 | GCK (0.35) | GCK | |
| SCHEMBL2644726 | 0.72 | GCK (0.55) | GCK | |
| SCHEMBL2645204 | 0.71 | GCK (0.45) | GCK | |
| SCHEMBL2645953 | 0.71 | GCK (0.44) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799820-B2 | 2-Heterocycle-substituted indole derivatives for treating diabetes and associated conditions | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-09-21 | — | — | US | claimed |