⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632982 | 0.78 | — | — | |
| SCHEMBL17319720 | 0.73 | — | — | |
| SCHEMBL9346 | 0.67 | — | — | |
| SCHEMBL6995987 | 0.65 | — | — | |
| SCHEMBL17102125 | 0.62 | — | — | |
| SCHEMBL17244 | 0.62 | — | — | |
| SCHEMBL14876768 | 0.62 | — | — | |
| SCHEMBL237047 | 0.62 | — | — | |
| SCHEMBL1364694 | 0.60 | — | — | |
| SCHEMBL5899334 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284660-A1 | HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. | 2021-09-16 | — | — | US | claimed |
| CN-112805280-A | Heteroaryl compounds for the treatment of huntington's disease | PTC医疗公司 | 2021-05-14 | — | — | CN | claimed |
| EP-3814345-A1 | HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2021-05-05 | — | — | EP | claimed |
| US-9796708-B2 | Pyrrolo [2,3-B] pyridine CDK9 kinase inhibitors | ABBVIE INC. (US) | 2017-10-24 | — | — | US | claimed |
| US-20160060257-A1 | PYRROLO [2,3-B] PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2016-03-03 | — | — | US | claimed |
| EP-2970278-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014139328-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-09-18 | — | — | WO | claimed |
| US-12030858-B2 | PARP inhibitors for treating cancer and asthma | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| EP-3843726-B1 | PARP INHIBITORS FOR TREATING CANCER AND ASTHMA | UNIV OREGON HEALTH & SCIENCE (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-3897630-B1 | THIENOPYRIDINE INHIBITORS OF RIPK2 | CELGENE CORP (US) | 2024-01-10 | — | — | EP | disclosed |
| CN-117222625-A | Substituted pyridazinones, salts or N-oxides thereof and their use as herbicidal agents | 拜耳公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-110799511-B | Herbicidal 3-phenylisoxazoline-5-carboxamides of tetrahydro-and dihydrofurancarboxamides | 拜耳公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20210347741-A1 | PARP INHIBITORS FOR TREATING CANCER AND ASTHMA | OREGON HEALTH & SCIENCE UNIVERSITY | 2021-11-11 | — | — | US | disclosed |
| WO-2015091934-A1 | OXINDOLE DERIVATIVES CARRYING AN AMINE-SUBSTITUTED PIPERIDYL-AZETIDINYL SUBSTITUENT AND USE THEREOF FOR TREATING VASOPRESSINE-RELATED DISEASES | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2014139328-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-1613607-B1 | BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS | BASF SE (DE) | 2013-01-09 | — | — | EP | disclosed |
| US-7741485-B2 | Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds | BASF AKTIENGESELLSCHAFT (DE) | 2010-06-22 | — | — | US | disclosed |
| US-20060211577-A1 | Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-21 | — | — | US | disclosed |
| EP-1613607-A1 | BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS | BASF Aktiengesellschaft (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004089914-A1 | BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | WO | disclosed |