⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15052806 | 0.70 | — | — | |
| SCHEMBL718003 | 0.70 | — | — | |
| SCHEMBL28122119 | 0.69 | — | — | |
| SCHEMBL17113797 | 0.64 | — | — | |
| SCHEMBL17113645 | 0.64 | — | — | |
| SCHEMBL17113799 | 0.64 | — | — | |
| SCHEMBL975833 | 0.57 | — | — | |
| SCHEMBL24637544 | 0.55 | — | — | |
| SCHEMBL1446567 | 0.55 | — | — | |
| SCHEMBL20195637 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101531-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2024-03-28 | — | — | US | disclosed |
| CN-105263941-A | Alkyl esters of 2- { [ (2R,3S,5R) -5- (4-amino-2-oxo-2H-pyrimidin-1-yl) -3-hydroxy-tetrahydro-furan-2-ylmethoxy ] -phenoxy-phosphorylamino } -propionic acid, nucleoside inhibitors of HCV RNA-polymerase NS5B, processes for their preparation and their use | IVACHTCHENKO ALEXANDRE VASILIEVICH | 2016-01-20 | — | — | CN | disclosed |
| CN-104829671-A | Gemcitabine/FTA/furazan conjugate in NO-donor type, preparation method and application | UNIV NANTONG | 2015-08-12 | — | — | CN | disclosed |
| CN-104693257-A | Benzenesulfonyl furazan modified gemcitabine derivative and preparation method and use thereof | UNIV NANTONG | 2015-06-10 | — | — | CN | disclosed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |