Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.62 |
| ▸ | PDE4A | P27815 | 15/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670201 | 0.92 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3679847 | 0.92 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5049520 | 0.91 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3672406 | 0.91 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3555709 | 0.89 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3549464 | 0.89 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3672014 | 0.89 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3677039 | 0.87 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3673863 | 0.87 | PDE4A (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3549578 | 0.87 | PDE4A (0.63) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825147-B2 | Inhibitors of phosphodiesterase type-IV | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-02 | — | — | US | disclosed |
| EP-1663999-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES, LTD. (IN) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005021515-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | WO | disclosed |