⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28064140 | 0.97 | CYP1A2 (0.50) | — | |
| Ammonia Solution, Strong SCHEMBL3052719 | 0.97 | CYP1A2 (0.50) | — | |
| Ammonia Solution, Strong SCHEMBL28116738 | 0.97 | CYP1A2 (0.50) | — | |
| Ammonia Solution, Strong SCHEMBL353931 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL354204 | 0.97 | CYP1A2 (0.50) | — | |
| SCHEMBL9954 | 0.96 | — | — | |
| SCHEMBL28350494 | 0.96 | CYP1A2 (0.48) | — | |
| SCHEMBL25446788 | 0.93 | CYP1A2 (0.52) | — | |
| SCHEMBL4576671 | 0.93 | CYP1A2 (0.52) | — | |
| SCHEMBL18078965 | 0.93 | CYP1A2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139908-A | Mannich bases with a high renewable carbon content | SIKA技术股份公司 | 2024-06-04 | — | — | CN | disclosed |
| US-20140329746-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2014-11-06 | — | — | US | disclosed |
| US-8835654-B2 | Method and compositions for treating amyloid-related diseases | BHI LIMITED PARTNERSHIP (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| US-8044100-B2 | Methods and compositions for treating amyloid-related diseases | BELLUS HEALTH INC. (CA) | 2011-10-25 | — | — | US | disclosed |
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| US-20060223855-A1 | reduces or inhibits amyloid fibril formation, organ specific dysfunction (e.g., neurodegeneration), or cellular toxicity | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-10-05 | — | — | US | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |
| US-4962129-A | INJECTING 3-HEPTANOL, 3-PENTANOL, 3-NONANOL OR 5-NONANOL IN VEGETABLE OIL | Avram, Elena (US) | 1990-10-09 | — | — | US | disclosed |