Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548586 | 1.00 | KCNH2 (0.42) | KCNH2SLC2A1 | |
| SCHEMBL3544549 | 0.92 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3544554 | 0.92 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3548782 | 0.92 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3548786 | 0.92 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3329893 | 0.83 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL3329888 | 0.83 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL3548642 | 0.83 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL3548647 | 0.83 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL13315217 | 0.82 | KCNH2 (0.42) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732461-B2 | (4S)-4-({4-[(2,3-Dihydro[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)amino]-1-piperidinyl}methyl)-3-fluoro-4-hydroxy-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one, used in the treatment of bacterial infections caused by a wide range of organisms including both gramnegative and grampositive bacteria | GLAXO GROUP LIMITED (GB) | 2010-06-08 | — | — | US | disclosed |
| US-20090137568-A1 | Tryclic Nitrogen Containing Compounds and their Use as Antibacterials | GLAXO GROUP LIMITED | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137568-A1 | Tryclic Nitrogen Containing Compounds and their Use as Antibacterials | NRDC, NACA, ASNS | KCNH2 2161/4885SLC2A1 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.