Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.68 |
| ▸ | CDK4 | P11802 | 6/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.68 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | AKT2 | P31751 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | FRK | P42685 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413105 | 0.87 | MAPK13 (0.53) | CDK2CDK4CCNE1MAPK13MAPK14 | |
| SCHEMBL409790 | 0.87 | MAPK13 (0.53) | CDK2CDK4CCNE1MAPK13MAPK14 | |
| SCHEMBL5278215 | 0.87 | MAPK13 (0.53) | CDK2CDK4CCNE1MAPK13MAPK14 | |
| SCHEMBL3550097 | 0.84 | MAPK14 (0.52) | CDK2CDK4CCNE1MAPK13MAPK14 | |
| SCHEMBL3556311 | 0.81 | DYRK1A (0.56) | CDK2CDK4MAPK13MAPK14MAPK12 | |
| SCHEMBL3549577 | 0.79 | CDK2 (0.43) | CDK2CDK4CCNE1MAPK13MAPK14 | |
| SCHEMBL5138420 | 0.77 | CDK2 (0.53) | CDK2CDK4CCNE1MAPK13MAPK14 | |
| SCHEMBL4317834 | 0.77 | CDK2 (1.00) | CDK2CDK4CCNE1CDK1KDM4E | |
| SCHEMBL1684643 | 0.77 | CDK2 (0.86) | CDK2CDK4CCNE1PRKD3MAP4K4 | |
| SCHEMBL21208238 | 0.76 | CDK2 (0.74) | CDK2CDK4CCNE1PRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718801-B2 | Substituted imidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070894-A1 | Novel Substituted Imidazole Derivative | PLK1, CDK1, CDK11A | CDK2 72/4885CDK4 39/4885CCNE1 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.