Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | CTSD | P07339 | 6/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2085042 | 0.92 | BACE1 (0.46) | BACE1KCNH2CTSDBACE2 | |
| Trifluoroacetic Acid SCHEMBL2085701 | 0.92 | BACE1 (0.45) | BACE1KCNH2CTSDBACE2 | |
| SCHEMBL3555713 | 0.89 | BACE1 (0.49) | BACE1KCNH2CTSDBACE2 | |
| SCHEMBL3547201 | 0.89 | BACE1 (0.49) | BACE1KCNH2CTSDBACE2 | |
| Trifluoroacetic Acid SCHEMBL2085105 | 0.87 | BACE1 (0.45) | BACE1KCNH2CTSDBACE2 | |
| Trifluoroacetic Acid SCHEMBL2085905 | 0.85 | BACE1 (0.41) | BACE1KCNH2CTSDBACE2 | |
| SCHEMBL3551247 | 0.84 | BACE1 (0.50) | BACE1KCNH2CTSDBACE2 | |
| Trifluoroacetic Acid SCHEMBL2086239 | 0.84 | BACE1 (0.47) | BACE1KCNH2CTSDBACE2 | |
| Trifluoroacetic Acid SCHEMBL2083989 | 0.84 | BACE1 (0.39) | BACE1KCNH2CTSDBACE2 | |
| Trifluoroacetic Acid SCHEMBL2085131 | 0.84 | BACE1 (0.39) | BACE1KCNH2CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855213-B2 | Compounds | ASTRAZENECA AB (SE) | 2010-12-21 | — | — | US | disclosed |