SCHEMBL3550396

SCHEMBL3550396

Cc1ccc(N(N)S(=O)(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
CA1 P00915 6/20 0.41
CA2 P00918 6/20 0.41
CA9 Q16790 4/20 0.41
CA12 O43570 4/20 0.41
CA3 P07451 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
ALDH1A1 P00352 4/20 0.41
TSHR P16473 1/20 0.41
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
GAA P10253 2/20 0.39
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19651773 0.80 MAPT (0.45) MAPTMCOLN3CA1CA2CA9
Hydrochloric Acid SCHEMBL27969717 0.78 TSHR (0.46) MAPTCA1CA2CA9CA12
SCHEMBL10975510 0.78 CA1 (0.47) MAPTCA1CA2CA9CA12
SCHEMBL1527692 0.77 TSHR (0.42) MAPTCA1CA2CA9CA12
SCHEMBL11598690 0.77 MAPT (0.47) MAPTMCOLN3CA1CA2CA9
SCHEMBL7946990 0.77 MAPT (0.62) MAPTMCOLN3CA1CA2CA9
SCHEMBL11830414 0.76 CA1 (0.46) MAPTCA1CA2CA9CA12
Sulfuric Acid SCHEMBL27953345 0.76 TSHR (0.41) MAPTCA1CA2CA9CA12
SCHEMBL28787889 0.74 MAPT (0.44) MAPTMCOLN3CA1CA2CA9
P-Xylene SCHEMBL2456088 0.72 GAA (0.58) CA1CA2CA9CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508555-B1 Process for producing pre-expandable plastic beads and beads obtainable according to said process ELECTROLUX HOME PROD CORP (BE) 2015-05-13 EP claimed
EP-2508555-A1 Process for producing pre-expandable plastic beads and beads obtainable according to said process Electrolux Home Products Corporation N.V. (BE) 2012-10-10 EP claimed
CN-107973790-A Heterocyclic FXR conditioning agent 合帕吉恩治疗公司 2018-05-01 CN disclosed
EP-2508555-B1 Process for producing pre-expandable plastic beads and beads obtainable according to said process ELECTROLUX HOME PROD CORP (BE) 2015-05-13 EP disclosed
EP-2508555-A1 Process for producing pre-expandable plastic beads and beads obtainable according to said process Electrolux Home Products Corporation N.V. (BE) 2012-10-10 EP disclosed
US-7851644-B2 Heterocyclic metallocenes and polymerization catalysts BASELL POLYOLEFINE GMBH (DE) 2010-12-14 US disclosed
US-20090286945-A9 Heterocyclic metallocenes and polymerization catalysts EWEN JOHN A 2009-11-19 US disclosed
US-20080090978-A1 Heterocyclic metallocenes and polymerization catalysts EWEN JOHN A 2008-04-17 US disclosed
US-7238818-B2 Heterocyclic metallocenes and polymerization catalysts BASELL POLYOLEFINE GMBH (DE) 2007-07-03 US disclosed
EP-1327636-B1 Heterocyclic metallocenes and polymerisation catalysts BASELL POLYOLEFINE GMBH (DE) 2006-01-11 EP disclosed
US-20050192418-A1 Heterocyclic metallocenes and polymerization catalysts EQUISTAR CHEMICALS, LP 2005-09-01 US disclosed
EP-1327636-A2 Heterocyclic metallocenes and polymerisation catalysts Basell Polyolefine GmbH (DE) 2003-07-16 EP disclosed
EP-0938491-B1 HETEROCYCLIC METALLOCENES AND POLYMERIZATION CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2003-05-07 EP disclosed
EP-0938491-A1 HETEROCYCLIC METALLOCENES AND POLYMERIZATION CATALYSTS Montell Technology Company B.V. (NL) 1999-09-01 EP disclosed
WO-1998022486-A1 HETEROCYCLIC METALLOCENES AND POLYMERIZATION CATALYSTS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1998-05-28 WO disclosed
EP-0083435-A2 Moulded body with a pressure-moulded polyester-impregnated fibrous sheet of coconut, cotton or jute and method for its production ERPE - Ernst Pelz - Vertriebs GmbH + Co. - Verwaltungs KG (DE) 1983-07-13 EP disclosed
US-4045169-A FLUORESCENT DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed
US-3957815-A 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286945-A9 Heterocyclic metallocenes and polymerization catalysts GAK, ZYX, POLK MAPT 4608/4885MCOLN3 613/4885CA1 3016/4885
US-20050192418-A1 Heterocyclic metallocenes and polymerization catalysts GAK, INTS9, ZYX MAPT 4628/4885MCOLN3 864/4885CA1 2869/4885
US-20080090978-A1 Heterocyclic metallocenes and polymerization catalysts GAK, ZYX, POLK MAPT 4608/4885MCOLN3 613/4885CA1 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.