Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926864 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759322 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12373191 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759260 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759258 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759262 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12759261 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9301837 | 0.95 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL64810 | 0.93 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7127653 | 0.92 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3820 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260131506-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-05-14 | — | — | US | claimed |
| US-12595368-B2 | UV/HEVL-filtering contact lenses | ALCON INC. (CH) | 2026-04-07 | — | — | US | claimed |
| EP-4713721-A1 | UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-03-25 | — | — | EP | claimed |
| EP-3759528-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2026-03-04 | — | — | EP | claimed |
| US-20260042268-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-20260042269-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC (CH) | 2026-02-12 | — | — | US | claimed |
| US-12539650-B2 | Method for making embedded hydrogel contact lenses | ALCON INC. (CH) | 2026-02-03 | — | — | US | claimed |
| EP-4657144-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| EP-4657145-A2 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | Alcon Inc. (CH) | 2025-12-03 | — | — | EP | claimed |
| US-12448516-B2 | Silicone hydrogel contact lenses | INTEROJO INC. (KR) | 2025-10-21 | — | — | US | claimed |
| US-4988788-A | Room temperature-curable coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | claimed |
| US-4808682-A | BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | claimed |
| EP-0277555-A2 | Copolymers with 0-nitrocarbinol ester groups, and process for preparing two-layer resists and semiconductor devices | BASF Aktiengesellschaft (DE) | 1988-08-10 | — | — | EP | claimed |
| EP-0252603-A2 | Adhesives for ceramics and processes for the bonding of ceramics using same | MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-01-13 | — | — | EP | claimed |
| EP-0216074-A2 | Polyvinyl alcohol derivatives and crosslinked hydrogel contact lenses made therefrom | CIBA-GEIGY AG (CH) | 1987-04-01 | — | — | EP | claimed |
| US-4500695-A | Silicone-vinyl acetate composition for contact lenses | IVANI EDWARD J | 1985-02-19 | — | — | US | claimed |
| US-4454295-A | CURSING WITH AN UNSATURATED SILICONE | UCO OPTICS, INC. (US) | 1984-06-12 | — | — | US | claimed |
| EP-0108886-A2 | Silicone-containing hard contact lens materials having increased oxygen permeability | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | claimed |
| US-4410674-A | Silicone-vinyl acetate composition for contact lenses | IVANI EDWARD J | 1983-10-18 | — | — | US | claimed |
| US-4395496-A | UNSATURATED ORGANOSILICON COMPOUND, CONTACT LENSES | UCO OPTICS, INC. (US) | 1983-07-26 | — | — | US | claimed |