Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768876 | 0.85 | TP53 (0.52) | MAPTTP53 | |
| SCHEMBL2786779 | 0.82 | MAPT (0.43) | MAPTTP53POLBSTK17BHTR2C | |
| SCHEMBL3564260 | 0.76 | MAPT (0.44) | MAPTTP53POLBSTK17BHTR2C | |
| SCHEMBL18727404 | 0.75 | MAPT (0.52) | MAPTTP53POLBSTK17BHTR2C | |
| SCHEMBL21240884 | 0.73 | MAPT (0.46) | MAPTTP53POLBSTK17BHTR2C | |
| SCHEMBL2787494 | 0.73 | TP53 (0.40) | MAPTTP53POLBHTR2CLMNA | |
| SCHEMBL2437851 | 0.69 | TP53 (0.56) | MAPTTP53POLBLMNAMEN1 | |
| SCHEMBL2440241 | 0.69 | SMN1; SMN2 (0.58) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL2441879 | 0.68 | MAPT (0.46) | MAPTTP53POLBHTR2CTDP1 | |
| SCHEMBL2440202 | 0.68 | SMN1; SMN2 (0.68) | MAPTTP53LMNAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696238-B2 | Substituted benzo[d]isoxazol-3-yl amine compounds as analgesics | GRUENENTHAL GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | GRUENENTHAL GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | KCNQ1, KCNQ2, KCNQ3 | MAPT 2492/4885TP53 4784/4885POLB 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.