Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193601 | 0.89 | MEN1 (0.50) | CYP3A4MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL27347358 | 0.85 | MEN1 (0.54) | CYP3A4MEN1KMT2ASMN1; SMN2ABCB11 | |
| Chlorobenzilate SCHEMBL28048828 | 0.85 | MEN1 (0.60) | CYP3A4MEN1KMT2ASMN1; SMN2ABCB11 | |
| Chlorobenzilate SCHEMBL73255 | 0.85 | MEN1 (0.60) | CYP3A4MEN1KMT2ASMN1; SMN2ABCB11 | |
| Chlorobenzilate SCHEMBL6243435 | 0.82 | MEN1 (0.54) | CYP19A1CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3556980 | 0.79 | CYP19A1 (0.64) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8330075 | 0.76 | MAPK1 (0.49) | CYP19A1CYP3A4MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL1225868 | 0.76 | TDP1 (0.56) | CYP19A1CYP3A4MAPK1SMN1; SMN2CYP1A2 | |
| Chlorobenzilate SCHEMBL29993079 | 0.76 | KMT2A (0.48) | CYP19A1CYP3A4MEN1KMT2AABCB11 | |
| SCHEMBL2763579 | 0.75 | POLB (0.62) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727998-B2 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MSD K.K. (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1595867-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS CONTAINING PIPERIDINE DERIVATIVES AS THE ACTIVE INGREDIENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MCHR1, MC1R, PRLHR | CYP19A1 156/4885CYP3A4 1270/4885CYP3A5 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.