Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.58 |
| ▸ | PDE4A | P27815 | 14/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047903 | 0.89 | PDE4A (0.62) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL3543669 | 0.88 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL3676490 | 0.87 | PDE4A (0.61) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL3669560 | 0.85 | PDE4A (0.59) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL3555709 | 0.85 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3679971 | 0.85 | PDE4A (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3677699 | 0.83 | PDE4D (0.56) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL3675100 | 0.82 | PDE4A (0.62) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL3673799 | 0.82 | PDE4D (0.55) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL3672011 | 0.82 | PDE4A (0.62) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825147-B2 | Inhibitors of phosphodiesterase type-IV | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-02 | — | — | US | claimed |