⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23131 | 0.76 | — | — | |
| SCHEMBL27959495 | 0.73 | — | — | |
| Water SCHEMBL27500796 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL27397580 | 0.73 | — | — | |
| Fluoride SCHEMBL27833372 | 0.73 | — | — | |
| Propionic Acid SCHEMBL3759122 | 0.70 | — | — | |
| Bromomethane SCHEMBL27300367 | 0.70 | — | — | |
| SCHEMBL28412126 | 0.70 | — | — | |
| Propionic Acid SCHEMBL28485688 | 0.70 | FFAR3 (0.83) | — | |
| Propionic Acid SCHEMBL290 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411004-A1 | USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS | National University of Singapore (SG) | 2012-02-01 | — | — | EP | disclosed |
| US-20120015923-A1 | USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-01-19 | — | — | US | disclosed |
| WO-2010110748-A1 | USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2010-09-30 | — | — | WO | disclosed |
| US-6576662-B2 | Novel derivatives of andrographolide | DR. REDDY'S LABORATORIES LIMITED (IN) | 2003-06-10 | — | — | US | disclosed |
| US-6486196-B2 | ANDROGRAPHOLIDE DERIVATIVES USEFUL FOR TREATING DIABETES II, CANCER, PSORIASIS, HIV INFECTIONS, RESTENOSIS, ATHEROSCLEROSIS, VIRAL INFECTIONS, MALERIA, BACTERIAL INFECTIONS, IMMUNOMODULATION, LIVER AND HEART DISORDERS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-11-26 | — | — | US | disclosed |
| US-20020016324-A1 | Compounds having anticancer activity : process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION | 2002-02-07 | — | — | US | disclosed |
| US-20020016363-A1 | Novel anticancer compounds : process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION | 2002-02-07 | — | — | US | disclosed |
| WO-2001085709-A2 | NEW COMPOUNDS HAVING ANTICANCER ACTIVITY: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001085710-A1 | NOVEL ANTICANCER COMPOUNDS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-11-15 | — | — | WO | disclosed |