Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.67 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PAK4 | O96013 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | LTK | P29376 | 2/20 | 0.41 |
| ▸ | GRK5 | P34947 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556400 | 1.00 | HSP90AB1 (0.67) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL3556403 | 1.00 | HSP90AB1 (0.67) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL2606627 | 0.89 | HSP90AB1 (0.67) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL13347439 | 0.88 | HSP90AB1 (0.66) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL2605051 | 0.88 | HSP90AB1 (0.68) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL2605057 | 0.87 | HSP90AB1 (0.65) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL2310179 | 0.87 | HSP90AB1 (0.64) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL2310173 | 0.87 | HSP90AB1 (0.64) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL2605027 | 0.87 | HSP90AB1 (0.71) | HSP90AB1NUDT1TNKSJAK2GSK3B | |
| SCHEMBL2605059 | 0.86 | HSP90AB1 (0.61) | HSP90AB1NUDT1TNKSGSK3BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674795-B2 | Fluorene derivatives, composition containing said derivatives and the use thereof | AVENTIS PHARMA SA (FR) | 2010-03-09 | — | — | US | disclosed |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | HSP90B1, HSP90AB1, HSP90AA1 | HSP90AB1 2/4885NUDT1 3139/4885TNKS 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.