⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3999852 | 0.97 | — | — | |
| SCHEMBL14657485 | 0.68 | — | — | |
| SCHEMBL10441274 | 0.68 | — | — | |
| SCHEMBL4484476 | 0.68 | — | — | |
| SCHEMBL3543692 | 0.68 | — | — | |
| SCHEMBL250449 | 0.68 | — | — | |
| SCHEMBL11560167 | 0.68 | — | — | |
| SCHEMBL10840218 | 0.66 | — | — | |
| SCHEMBL9355593 | 0.64 | — | — | |
| SCHEMBL10890847 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119242631-A | Multiple exon skipping compositions for DMD | 萨雷普塔治疗公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-112574988-A | Multi-exon skipping compositions for DMD | 萨雷普塔治疗公司 | 2021-03-30 | — | — | CN | disclosed |
| US-9833520-B2 | Labeled, non-peptidic, multivalent integrin antagonist compounds; methods for synthesis and uses thereof | THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) | 2017-12-05 | — | — | US | disclosed |
| EP-2597087-B1 | Dihydrooxazine and tetrahydropyrimidine derivatives as BACE 1 inhibitors | SHIONOGI & CO (JP) | 2016-03-30 | — | — | EP | disclosed |
| US-20150210680-A1 | AMINODIHYDROTHIAZINE DERIVATIVES | SHIONOGI & CO (JP) | 2015-07-30 | — | — | US | disclosed |
| US-9029358-B2 | Aminodihydrothiazine derivatives | SHIONOGI & CO., LTD. (JP) | 2015-05-12 | — | — | US | disclosed |
| EP-2612854-B1 | Aminothiazolidine and aminotetrahydrothiazepine derivatives as BACE 1 inhibitors | SHIONOGI & CO (JP) | 2015-04-29 | — | — | EP | disclosed |
| US-8895548-B2 | Pharmaceutical composition for treating alzheimer's disease | SHIONOGI & CO., LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8815851-B2 | Aminodihydrothiazine derivatives | SHIONOGI & CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| EP-1942105-B1 | AMINODIHYDROTHIAZINE DERIVATIVE | SHIONOGI & CO (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-0042279-B1 | N-ARYL-N'((1,4,5,6-TETRAHYDROPYRIMIDIN-2-YL) OR (4,5,6,7-TETRAHYDRO-1-H-1, 3-DIAZEPIN-2-YL)UREAS FOR INTESTINAL DISORDERS AND AS ANTIHYPERTENSIVES | McNeilab, Inc. (US) | 1985-11-13 | — | — | EP | disclosed |
| EP-0024776-B1 | 4-PHENYL AND 5-PHENYL-1,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES, AND PROCESS FOR PREPARING SAID DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4466966-A | N-aryl-N'-(1,4,5,6-tetrahydropyrimidin-2-yl)ureas for intestinal disorders | MCNEILAB, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4383090-A | HIGH SPEED; COCURING AGENT OF POLYAMIDE-POLYLACTAM COPOLYMER; FILMS; CASTINGS; POTTING; ADHESIVES | DIAMOND SHAMROCK CORPORATION (US) | 1983-05-10 | — | — | US | disclosed |
| EP-0075827-A2 | Polyepoxide curing by polymercaptans plus catalytic co-curing agents | DIAMOND SHAMROCK CHEMICALS COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| US-4322421-A | 4-Phenyl-and 5-phenyl-1,4,5,6-tetrahydro-pyrimidine derivatives | SYNTEX (U.S.A.) INC. (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0042279-A2 | N-aryl-N'((1,4,5,6-tetrahydropyrimidin-2-yl) or (4,5,6,7-tetrahydro-1-H-1, 3-diazepin-2-yl)ureas for intestinal disorders and as antihypertensives | McNeilab, Inc. (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4285948-A | ADMINISTERING CARDIOTONIC AGENTS | MCNEILAB, INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4261995-A | DISORDERS OF CENTRAL NERVOUS SYSTEM AND CARDIOVASCULAR SYSTEM; HYPOTENSIVE | SYNTEX (U.S.A.) INC. (US) | 1981-04-14 | — | — | US | disclosed |
| EP-0024776-A1 | 4-Phenyl and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, pharmaceutical compositions containing said derivatives, and process for preparing said derivatives | SYNTEX (U.S.A.) INC. (US) | 1981-03-11 | — | — | EP | disclosed |