SCHEMBL355986

SCHEMBL355986

CCC(C)c1cccc(O)c1C(C)CC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.70
GABRA1 P14867 4/20 0.48
GABRB2 P47870 3/20 0.48
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
RORC P51449 1/20 0.44
HPGD P15428 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
FAAH O00519 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
GABRB1 P18505 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2C P28335 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560269 1.00 TSHR (0.70) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL31330562 1.00 TSHR (0.70) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL560097 1.00 TSHR (0.70) TSHRGABRA1GABRB2HDAC4HDAC2
Benzene SCHEMBL1835281 0.98 TSHR (0.68) TSHRGABRA1GABRB2HDAC4HDAC2
Ethylene SCHEMBL15018849 0.96 TSHR (0.66) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL3576125 0.87 TSHR (0.61) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL28343869 0.85 TSHR (0.59) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL2371854 0.85 TSHR (0.58) TSHRGABRA1GABRB2HDAC4HDAC2
Propylene Oxide SCHEMBL15018141 0.83 TSHR (0.50) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL282162 0.83 TSHR (1.00) TSHRGABRA1GABRB2HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119582504-A Dampproof high-voltage submersible motor winding wire and preparation method thereof 河北国潜线缆有限责任公司 2025-03-07 CN claimed
CN-117186446-A Annular phenolic colloid particles, preparation method thereof and annular carbon colloid particles prepared by using annular phenolic colloid particles 中国科学院化学研究所 2023-12-08 CN claimed
EP-3702353-B1 ANTIFUNGAL COMPOSITIONS MYCOVIA PHARMACEUTICALS INC (US) 2023-07-05 EP claimed
US-20210360921-A1 ANTIFUNGAL COMPOUNDS Mycovia Pharmaceuticals, Inc. (US) 2021-11-25 US claimed
US-10919864-B2 5-fluoro-4-imino-3(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1H)-one and processes for their preparation ADAMA MAKHTESHIM LTD. (IL) 2021-02-16 US claimed
EP-3702353-A1 ANTIFUNGAL COMPOSITIONS Viamet Pharmaceuticals (NC), Inc. (US) 2020-09-02 EP claimed
US-20200148649-A1 5-FLUORO-4-IMINO-3(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE AND PROCESSES FOR THEIR PREPARATION ADAMA MAKHTESHIM LTD. (IL) 2020-05-14 US claimed
CN-106977462-B 5-fluoro-4-imino-3- (substituted) -3, 4-dihydropyrimidin-2 (1H) one derivatives 阿达玛马克西姆股份有限公司 2020-04-28 CN claimed
US-20190308941-A1 5-FLUORO-4-IMINO-3(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE AND PROCESSES FOR THEIR PREPARATION ADAMA MAKHTESHIM LTD. (IL) 2019-10-10 US claimed
EP-2632265-B1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM AND ORYZALIN DOW AGROSCIENCES LLC (US) 2017-01-11 EP claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
WO-2003077894-A1 FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2003-09-25 WO claimed
US-20030176513-A1 Fluorine-substituted alkyl phenol compounds and their uses IOWA RESEARCH FOUNDATION, UNIVERSITY OF 2003-09-18 US claimed
US-5344863-A Polyolefin, dispersant and phenolic derivative SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1994-09-06 US claimed
US-5043379-A Vinyl chloride polymer; plasticizer; aromatic diisocyanate polymer to increase adhesiveness; thermal dissociation promoting agent KYPEISHA CHEMICAL CO., LTD. (JP) 1991-08-27 US claimed
US-4087572-A COATING A COAL PILE WITH ORGANIC POLYMER LATEX AND SILICONE THE DOW CHEMICAL COMPANY (US) 1978-05-02 US claimed
US-4072790-A PACKAGING MEAT THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-02-07 US claimed
US-4057672-A Compounded polyvinyl chloride THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-11-08 US claimed
US-4012355-A HYDROPHOBIC THE DOW CHEMICAL COMPANY (US) 1977-03-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919864-B2 5-fluoro-4-imino-3(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1H)-one and processes for their preparation FLI1, PAICS, MCL1 TSHR 3688/4885GABRA1 3435/4885GABRB2 4169/4885
US-20200148649-A1 5-FLUORO-4-IMINO-3(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE AND PROCESSES FOR THEIR PREPARATION FLI1, PAICS, MCL1 TSHR 3688/4885GABRA1 3435/4885GABRB2 4169/4885
US-20030176513-A1 Fluorine-substituted alkyl phenol compounds and their uses AFF4, AFF1, AFF2 TSHR 1138/4885GABRA1 3412/4885GABRB2 4004/4885
US-20190308941-A1 5-FLUORO-4-IMINO-3(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE AND PROCESSES FOR THEIR PREPARATION PAICS, MCL1, FLI1 TSHR 3508/4885GABRA1 3076/4885GABRB2 4030/4885
US-20210360921-A1 ANTIFUNGAL COMPOUNDS CYP51A1, LSS, CYP7A1 TSHR 4448/4885GABRA1 1757/4885GABRB2 2967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.