SCHEMBL355992

SCHEMBL355992

CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.79
CHRM3 P20309 19/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645742 0.91 CHRM2 (0.80) CHRM2CHRM3
SCHEMBL24906748 0.91 CHRM2 (0.79) CHRM2CHRM3
SCHEMBL644910 0.91 CHRM2 (0.79) CHRM2CHRM3
SCHEMBL19996286 0.90 CHRM2 (0.78) CHRM2CHRM3
SCHEMBL356695 0.90 CHRM2 (0.72) CHRM2CHRM3
SCHEMBL13430601 0.89 CHRM2 (0.76) CHRM2CHRM3
SCHEMBL10015120 0.89 CHRM2 (0.71) CHRM2CHRM3
Revefenacin SCHEMBL356480 0.89 CHRM2 (1.00) CHRM2CHRM3
SCHEMBL644273 0.89 CHRM2 (0.76) CHRM2CHRM3
SCHEMBL266143 0.88 CHRM2 (0.71) CHRM2CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136550-A1 PROCESSES FOR PREPARING REVEFENACIN AND COMPOSITIONS COMPRISING THE SAME THERAVANCE BIOPHARMA R&D IP, LLC 2025-05-01 US disclosed
EP-2593429-B1 PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID THERAVANCE BIOPHARMA R & D IP LLC (US) 2015-06-03 EP disclosed
US-9035061-B2 Process for preparing a biphenyl-2-ylcarbamic acid THERAVANCE BIOPHARMA R&D IP, LLC (US) 2015-05-19 US disclosed
US-8754225-B2 Process for preparing a biphenyl-2-ylcarbamic acid THERAVANCE, INC. (US) 2014-06-17 US disclosed
US-20140121378-A1 PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID THERAVANCE, INC. (US) 2014-05-01 US disclosed
EP-2593429-A1 PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID Theravance, Inc. (US) 2013-05-22 EP disclosed
US-20120016130-A1 PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID THERAVANCE BIOPHARMA R&D IP, LLC 2012-01-19 US disclosed
WO-2012009166-A1 PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID THERAVANCE, INC. (US) 2012-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136550-A1 PROCESSES FOR PREPARING REVEFENACIN AND COMPOSITIONS COMPRISING THE SAME CYP4B1, KDM4B, CYP3A4 CHRM2 2542/4885CHRM3 1755/4885
US-20140121378-A1 PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID CYP4B1, KDM2B, CYP26B1 CHRM2 2217/4885CHRM3 2296/4885
US-20120016130-A1 PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID CYP4B1, KDM2B, CYP26B1 CHRM2 2217/4885CHRM3 2296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.