Hydroquinone

Hydroquinone

SCHEMBL356143

OCC1CCC(CO)CC1.OCCOCCO.Oc1ccc(O)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 10/20 0.58
ESR1 P03372 7/20 0.58
CYP3A4 P08684 2/20 0.58
CYP2C9 P11712 2/20 0.58
CYP2D6 P10635 1/20 0.51
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 1/20 0.35
APP P05067 1/20 0.34
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
ALDH2 P05091 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL408939 0.85 ESR2 (0.75) ESR2ESR1CYP3A4CYP2C9CYP2D6
Di(Hydroxyethyl)Ether SCHEMBL6264148 0.85 TSHR (0.56) ESR2ESR1CYP3A4CYP2C9CYP2D6
Di(Hydroxyethyl)Ether SCHEMBL28229544 0.83 TSHR (0.53) ESR2ESR1CYP3A4CYP2C9CYP2D6
Hydroquinone SCHEMBL109119 0.82 TSHR (0.59) ESR2ESR1CYP3A4TSHRMAPK1
Hydroquinone SCHEMBL56540 0.82 TSHR (0.59) ESR2ESR1CYP3A4TSHRMAPK1
Hydroquinone SCHEMBL1815638 0.80 TSHR (0.56) ESR2ESR1CYP3A4TSHRMAPK1
Hydroquinone SCHEMBL6051296 0.76 TSHR (0.50) CYP3A4TSHRMAPK1MEN1KMT2A
SCHEMBL578589 0.74 APP (0.48) CYP3A4MAPK1MEN1KMT2AAPP
1,6-Hexanediol SCHEMBL8674638 0.74 TSHR (0.48) CYP3A4TSHRMAPK1MEN1KMT2A
SCHEMBL11314262 0.74 TSHR (0.41) ESR2ESR1CYP3A4CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2271391-B1 URETERAL STENTS FOR RELEASE OF UROLOGICALLY BENEFICIAL AGENTS BOSTON SCIENT SCIMED INC (US) 2019-10-30 EP disclosed
US-10251741-B2 Ureteral stent with drug-releasing structure BOSTON SCIENTIFIC SCIMED, INC. (US) 2019-04-09 US disclosed
EP-2294105-B1 FIBER REINFORCED TPU COMPOSITES LUBRIZOL ADVANCED MAT INC (US) 2018-07-11 EP disclosed
US-20160361152-A1 URETERAL STENT WITH DRUG-RELEASING STRUCTURE BOSTON SCIENTIFIC SCIMED, INC. 2016-12-15 US disclosed
US-9445884-B2 Ureteral stent with drug-releasing structure BOSTON SCIENTIFIC SCIMED, INC. (US) 2016-09-20 US disclosed
US-9068076-B2 Fiber reinforced TPU composites LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-06-30 US disclosed
US-9029443-B2 Non halogen flame retardant thermoplastic polyurethane LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-05-12 US disclosed
US-8940056-B2 Ureteral stents for release of urologically beneficial agents BOSTON SCIENTIFIC SCIMED, INC. (US) 2015-01-27 US disclosed
US-20140349111-A1 Non Halogen Flame Retardant Thermoplastic Polyurethane LUBRIZOL ADVANCED MAT INC (US) 2014-11-27 US disclosed
US-20140214175-A1 URETERAL STENT WITH DRUG-RELEASING STRUCTURE BOSTON SCIENTIFIC SCIMED, INC. (US) 2014-07-31 US disclosed
US-20070292649-A1 Multilayered Articles Having Biocompatibility And Biostability Characteristics LUBRIZOL ADVANCED MATERIALS, INC. (US) 2007-12-20 US disclosed
US-7264858-B2 Multilayered articles having biocompatibility and biostability characteristics LUBRIZOL ADVANCED MATERIALS, INC. (US) 2007-09-04 US disclosed
WO-2006121549-A1 NON HALOGEN FLAME RETARDANT THERMOPLASTIC POLYURETHANE LUBRIZOL ADVANCED MATERIALS, INC. (US) 2006-11-16 WO disclosed
EP-1235878-B1 EXTRUDABLE POLYURETHANE COMPOSITIONS AND METHODS OF MAKING THEM NOVEON IP HOLDINGS CORP (US) 2005-12-28 EP disclosed
US-6777466-B2 WIRE, CABLE JACKET; MOLDING MATERIALS; TENSILE STRENGTH NOVEON IP HOLDINGS CORP. 2004-08-17 US disclosed
WO-2004039584-A1 MULTILAYERED ARTICLES HAVING BIOCOMPATIBILITY AND BIOSTABILITY CHARACTERISTICS NOVEON IP HOLDINGS CORP. (US) 2004-05-13 WO disclosed
US-20030166749-A1 Flame retardant thermoplastic polyurethane containing melamine cyanurate NOVEON, INC. 2003-09-04 US disclosed
US-6458880-B1 POLYESTERURETHANE COPOLYMERS WITH TALC FOR CRYSTALIZATION NOVEON IP HOLDINGS CORP. 2002-10-01 US disclosed
US-6297321-B1 Extrudable polyurethane compositions and methods THE B. F. GOODRICH COMPANY 2001-10-02 US disclosed
US-5110850-A Wires, cable jackets, blown films B. F. GOODRICH COMPANY (US) 1992-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10251741-B2 Ureteral stent with drug-releasing structure UTS2R, KDELR2, KDELR1 ESR2 329/4885ESR1 126/4885CYP3A4 3731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.