Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581966 | 0.78 | HDAC8 (0.45) | F10KMT2AMEN1HDAC8PTPN1 | |
| SCHEMBL3562002 | 0.76 | PTPN1 (0.58) | ALDH1A1HPGDLMNAHDAC8PTPN1 | |
| SCHEMBL30581791 | 0.74 | PTPN1 (0.46) | F10HDAC8PTPN1TACR1 | |
| SCHEMBL6585678 | 0.74 | PTPN1 (0.47) | F10KMT2AMEN1HDAC8PTPN1 | |
| SCHEMBL30582004 | 0.72 | PTPN1 (0.47) | F10HDAC8PTPN1TACR1 | |
| SCHEMBL4648949 | 0.72 | PTPN1 (0.45) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL24172862 | 0.72 | PTPN1 (0.47) | F10KMT2AMEN1HDAC8PTPN1 | |
| SCHEMBL30167025 | 0.72 | PTPN1 (0.47) | F10KMT2AMEN1HDAC8PTPN1 | |
| SCHEMBL3550883 | 0.72 | PTPN1 (0.47) | F10KMT2AMEN1HDAC8PTPN1 | |
| SCHEMBL30167036 | 0.72 | PTPN1 (0.47) | F10KMT2AMEN1HDAC8PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |