Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657409 | 1.00 | GCK (0.63) | GCK | |
| SCHEMBL2658090 | 0.92 | GCK (0.60) | GCK | |
| SCHEMBL3564385 | 0.92 | GCK (0.60) | GCK | |
| SCHEMBL2656335 | 0.91 | GCK (0.75) | GCK | |
| SCHEMBL8142670 | 0.91 | GCK (0.75) | GCK | |
| SCHEMBL2655283 | 0.91 | GCK (0.59) | GCK | |
| SCHEMBL3568479 | 0.91 | GCK (0.59) | GCK | |
| SCHEMBL2655279 | 0.91 | GCK (0.59) | GCK | |
| SCHEMBL2656587 | 0.90 | GCK (0.56) | GCK | |
| SCHEMBL14110354 | 0.90 | GCK (0.56) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934180-B1 | 3-CYCLYL-2-(4-SULFAMOYL-PHENYL)-N-CYCLYL-PROPIONAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF IMPAIRED GLUCOSE TOLERANCE AND DIABETES | NOVARTIS AG (CH) | 2012-12-05 | — | — | EP | claimed |
| US-7795257-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-09-14 | — | — | US | claimed |
| EP-1934180-B1 | 3-CYCLYL-2-(4-SULFAMOYL-PHENYL)-N-CYCLYL-PROPIONAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF IMPAIRED GLUCOSE TOLERANCE AND DIABETES | NOVARTIS AG (CH) | 2012-12-05 | — | — | EP | disclosed |