Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111141 | 0.78 | PARP1 (0.33) | PARP1 | |
| SCHEMBL8525523 | 0.71 | POLB (0.43) | POLBPARP1 | |
| SCHEMBL1107770 | 0.71 | POLB (0.43) | POLBPARP1 | |
| SCHEMBL10346048 | 0.68 | POLB (0.33) | POLBPARP1 | |
| SCHEMBL15188492 | 0.66 | MAOB (0.39) | POLBPARP1 | |
| SCHEMBL11972391 | 0.63 | ATM (0.42) | — | |
| SCHEMBL9877616 | 0.62 | POLB (0.41) | POLBPARP1 | |
| SCHEMBL171162 | 0.62 | ABCB1 (0.46) | POLBPARP1 | |
| SCHEMBL217130 | 0.62 | HTR2A (0.31) | — | |
| SCHEMBL353825 | 0.61 | PARP1 (0.40) | POLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277384-A2 | 1H-imidazole-5-carboxylic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-10 | — | — | EP | claimed |
| US-7838676-B2 | Beta-secretase modulators and methods of use | AMGEN INC. (US) | 2010-11-23 | — | — | US | disclosed |
| EP-0277384-A2 | 1H-imidazole-5-carboxylic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-10 | — | — | EP | disclosed |