Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3566808 | 0.96 | PTGER4 (0.62) | PTGER4HTR1AADRA1A | |
| SCHEMBL3564208 | 0.94 | PTGER4 (0.60) | PTGER4HTR1AADRA1A | |
| SCHEMBL3569685 | 0.94 | PTGER4 (0.71) | PTGER4HTR1AADRA1A | |
| SCHEMBL3564981 | 0.93 | PTGER4 (0.73) | PTGER4HTR1AADRA1A | |
| SCHEMBL3563601 | 0.93 | PTGER4 (0.70) | PTGER4HTR1AADRA1A | |
| SCHEMBL3564298 | 0.91 | PTGER4 (0.60) | PTGER4HTR1AADRA1A | |
| SCHEMBL3561366 | 0.89 | PTGER4 (0.73) | PTGER4HTR1AADRA1A | |
| SCHEMBL3567447 | 0.89 | PTGER4 (0.71) | PTGER4HTR1AADRA1A | |
| SCHEMBL3562737 | 0.87 | PTGER4 (0.66) | PTGER4HTR1AADRA1A | |
| SCHEMBL3567443 | 0.85 | PTGER4 (0.85) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732622-B2 | Naphthalene derivatives | GLAXO GROUP LIMITED (GB) | 2010-06-08 | — | — | US | disclosed |
| US-20080234358-A1 | E-series of prostaglandin (EP) receptors; [[4-(4,9-dipropoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl) phenyl]acetic acid | CONGREVE MILES STUART | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234358-A1 | E-series of prostaglandin (EP) receptors; [[4-(4,9-dipropoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl) phenyl]acetic acid | PTGER3, OPRL1, PTGER1 | PTGER4 21/4885HTR1A 217/4885ADRA1A 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.